医学
透明质酸
耐受性
不利影响
填料(材料)
外科
牙科
内科学
材料科学
复合材料
解剖
作者
Nowell Solish,Arthur Swift
出处
期刊:PubMed
日期:2011-02-01
卷期号:10 (2): 145-9
被引量:22
摘要
There have been few systematic investigations of the effectiveness, safety and tolerability of aesthetic lip augmentation using hyaluronic acid (HA) fillers.Evaluate the effectiveness of small gel particle hyaluronic acid filler (Restylane Injectable Gel [SGP-HA]; Medicis Aesthetics Inc., Scottsdale, AZ) in lip augmentation using the Medicis Lip Fullness Scale (MLFS). Assess subjective improvement in lip appearance using the Global Aesthetic Improvement Scale (GAIS).Investigators treated 21 adults. The primary efficacy endpoint was an increase in lip fullness at least one grade on MLFS at eight weeks post-treatment. Adverse events were reported using patient diaries.Sixteen of 18 evaluable subjects (89%) had an improvement at least one grade on MLFS in both lips. MLFS and GAIS scores were consistent, suggesting clinically significant aesthetic improvement. Adverse effects were transient and mostly mild to moderate in severity.Lip augmentation with SGP-HA was well tolerated and resulted in clinically meaningful increases in lip fullness.
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