Background: Malignant intestinal obstruction refers to intestinal obstruction caused by advanced primary tumors or secondary metastatic malignant tumors. Because surgical treatment cannot significantly improve the life cycle, non-surgical treatment is mostly used to improve the symptoms of intestinal obstruction; transanal intestinal obstruction catheter and transnasal intestinal obstruction catheter are palliative therapies for decompression and drainage. Transanal intestinal obstruction catheter is mostly used for rectal and left colon obstruction. Transnasal intestinal obstruction catheter is mostly used for small intestinal obstruction. The two catheters are generally used alone according to the site of obstruction and clinical manifestations, and there are few reports on the combined use of the two catheters. We try to use the two catheters to treat patients with complex conditions and explore a better treatment strategy for malignant intestinal obstruction.