Portfolio Selection and Management in Pharmaceutical Research and Development: Issues and Challenges

Portfolio management (PM) has been an area of attention and focus for the pharmaceutical industry since the late 1990s. Over the past 5 years, there has been an increased interest in PM as pharmaceutical pipelines become thinner, industry consolidation accelerates, and R&D funding lessens as a proportion of sales.1 In this article, I explore several simple and straightforward ways to manage the pharmaceutical portfolio. Clinical Pharmacology & Therapeutics (2011) 89 2, 300–303. doi:10.1038/clpt.2010.289