适体
生物传感器
纳米技术
纳米材料
灵活性(工程)
寡核苷酸
材料科学
DNA
化学
生物
分子生物学
数学
生物化学
统计
作者
Rongmei Kong,Xiaobing Zhang,Zhuo Chen,Weihong Tan
出处
期刊:Small
[Wiley]
日期:2011-07-04
卷期号:7 (17): 2428-2436
被引量:26
标识
DOI:10.1002/smll.201100250
摘要
Aptamers represent a class of single-stranded DNA or RNA oligonucleotides that play important roles in biosensing and biomedical applications. However, aptamers can gain more flexibility as molecular recognition tools by taking advantage of the unique chemical and physical properties provided by nanomaterials. Such aptamer-nanomaterial conjugates are having an increasing impact in the fields of biosensing, bioimaging, and therapy. The recent advances and limitations of aptamer-assembled nanomaterials in biosensing and biomedical applications are briefly introduced and discussed.
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