Bilateral vs. unilateral repetitive transcranial magnetic stimulation to treat neuropathic orofacial pain: A pilot study

Neuropathic orofacial pain can be caused by various disorders that originate in the central- or peripheral nervous system [1]. One of these disorders includes painful trigeminal neuropathy for which an effective management can be difficult to establish, when pharmacotherapy fails. This has led to the search for new treatment options, e.g., transcranial magnetic stimulation of the primary motor cortex (TMS). TMS uses electromagnetic induction to influence cortical excitability [2,3]. Orientation of the coil and stimulation intensity were found to influence neurons in a different fashion [4].