化学
抗氧化剂
聚乙烯醇
DPPH
羟基自由基
膜
纳米纤维
静电纺丝
水溶液
扫描电子显微镜
吸水率
色谱法
核化学
高分子化学
有机化学
化学工程
材料科学
生物化学
聚合物
复合材料
工程类
作者
Hualei Xu,Ziyan Wu,Dan Zhao,Haiyan Liang,Huanxiang Yuan,Changtao Wang
标识
DOI:10.1016/j.ijbiomac.2022.06.047
摘要
A novel nanofiber material incorporating hyaluronic acid (HA), crude huangshui polysaccharide (cHSP) and polyvinyl alcohol (PVA) were prepared to obtain dry facial masks (PVA/HA/cHSP) via electrospinning. The facial mask was characterized by scanning electron microscopy (SEM), water absorption and retention evaluation, in vitro release study, DPPH and hydroxyl free radical scavenging measurements, red blood cell hemolysis and chick embryo chorioallantoic membrane assay. The results suggested that the fiber mask was densely homogeneous, uniform and well distributed with a diameter <260 nm. Meanwhile, the water absorption rate was >300 %, DPPH and hydroxyl free radical half-inhibitory concentrations of cHSP aqueous solution scavenging were 0.2781 and 1.029 mg/mL, respectively. The PVA/HA/cHSP could retain the antioxidant capacity of cHSP, possessing simultaneous excellent moisture retention and oxidation resistance. Importantly, the mucous membrane irritation experiment indicated that it was mild and safe.
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