[Current status and changes of disease burden of cardio-cerebrovascular diseases in 1990 and 2016 for Beijing people].

Objective: To investigate the current status and changes of disease burden of cardio-cerebrovascular diseases in 1990 and 2016 for Beijing people. Methods: Using the results of the Global Burden of Diseases Study 2016 (GBD 2016) to describe deaths status and disease burden of cardio-cerebrovascular diseases in Beijing. The measurement index included the total deaths, years of life lost due to premature mortality (YLL), years lived with disability (YLD), and disability-adjusted years (DALY). Using the average world population from 2000 to 2025 as standard population to calculate the age-standardized mortality rate, DALY rate, YLL rate and YLD rate. Results: The age-standardized mortality rate of cardio-cerebrovascular diseases was 209.24 per 100 000. In 2016, DALY, YLL and YLD of cardio-cerebrovascular was 875.6, 733.6 and 142.0 thousand person-years, respectively, which has increased by 58.05%, 44.24% and 213.47%, respectively, than that in 1990. The age-standardized DALY rate and age-standardized YLL rate of cardio-cerebrovascular diseases in 2016 was 3 552.24 and 2 988.01 per 100 000 which has decreased by 47.90% and 52.43%, respectively, than that in 1990. The age-standardized YLD rate of cardio-cerebrovascular diseases in 2016 was 564.23 per 100 000 which increased by 5.10% than that in 1990. In 2016, the total death of cerebrovascular disease and ischemic heart disease was 17.6 thousand and 23.7 thousand, respectively. DALY was 396.3 and 393.6 thousand person-years in 2016, while 330.2 and 162.7 thousand person-years in 1990, which has increased by 20.02% and 141.92%, respectively. Conclusions: The disease burden of cardio-cerebrovascular disease is serious, especially the burden of cerebrovascular disease and ischemic heart disease. The disability burden of cerebrovascular disease is serious. The disease burden of ischemic heart disease has multiplied.目的： 调查1990年和2016年北京市心脑血管疾病负担及其变化情况。 方法： 利用2016年全球疾病负担研究数据，分析1990年和2016年北京市心脑血管疾病死亡情况和疾病负担。主要指标包括死亡人数、过早死亡损失寿命年（YLL）、伤残损失寿命年（YLD）和伤残调整寿命年（DALY），同时使用2000—2025年世界人口的平均人口作为标准人口，计算标化死亡率、DALY率、YLL率和YLD率。 结果： 2016年，北京市居民心脑血管病标化死亡率为209.24/10万；心脑血管病DALY、YLL和YLD分别为87.56、73.36和14.20万人年，较1990年分别增加了58.05%、44.24%和213.47%；标化DALY率和标化YLL率分别为3 552.24/10万和2 988.01/10万，较1990年分别下降47.90%和52.43%，标化YLD率为564.23/10万，较1990年增加5.10%。2016年，脑血管疾病和缺血性心脏病的死亡数分别为1.76万例和2.37万例；DALY分别为39.63和39.36万人年，较1990年（DALY分别为33.02和16.27万人年）分别增加20.02%和141.92%。 结论： 北京市心脑血管疾病负担重，其中以脑血管疾病和缺血性心脏病最为显著；脑血管疾病的伤残负担严重，缺血性心脏病的疾病负担成倍增长。.