Exposure to general anesthesia before 4 years of age did not affect growth and development: A nationwide retrospective cohort study using an early childhood health screening database

医学 儿科 队列 回顾性队列研究 十分位 倾向得分匹配 出生体重 注意缺陷多动障碍 情感(语言学) 外科 精神科 怀孕 内科学 哲学 统计 生物 遗传学 语言学 数学
作者
Eun Jin Ahn,Si Ra Bang
出处
期刊:International Journal of Surgery Open [Wolters Kluwer]
卷期号:25: 47-51 被引量:3
标识
DOI:10.1016/j.ijso.2020.07.001
摘要

ABSTRACT Introduction: There is little evidence that anesthetics are associated with neurotoxicity in children. In this study, we used a nationwide database to evaluate the association between general anesthesia and attention deficit/hyperactivity disorder (ADHD) in pediatric patients. Methods: We retrospectively analyzed data from the National Health Insurance Service-infant medical checkup cohort database. We included all pediatric patients born in 2008 and 2009 and classified them into two groups according to their history of exposure to general anesthesia. Group G included pediatric patients who had been exposed to general anesthesia at least once before 4 years of age. Group O included a 1:4 matched cohort based on birth weight, sex, and income decile. The primary outcome was the prevalence of ADHD. Secondary outcomes included head circumference, height, weight, visual and auditory development. Results: Among 17,451 participants, 315 (1.8%) underwent general anesthesia before 4 years of age. After propensity score matching, 1259 participants were selected in group O, with no significant differences between the groups in terms of birth weight, sex, income decile, and prematurity. Among all 1574 participants, 17 (1.08%) were diagnosed with ADHD, without a significant difference between the two groups ( P = 0.33). There was also no significant difference in head circumference, height, weight, auditory and visual development ( P = 0.43, 0.45, 0.49, 0.32, 0.13, respectively). Conclusion: Children who underwent surgery requiring general anesthesia before 4 years of age did not have an increased risk of ADHD or developmental disorders. Future studies should assess the association between duration of surgery and occurrence of ADHD. Highlights:
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
烟花应助杨诗梦采纳,获得10
刚刚
唐思远完成签到,获得积分10
刚刚
麻瓜小禾子完成签到,获得积分20
刚刚
czxchase发布了新的文献求助10
刚刚
Sean发布了新的文献求助10
刚刚
王羲之发布了新的文献求助10
1秒前
kinsley发布了新的文献求助10
1秒前
2秒前
风趣飞柏发布了新的文献求助10
2秒前
3秒前
3秒前
景三发布了新的文献求助10
3秒前
科研通AI2S应助和谐山灵采纳,获得10
3秒前
豆豆发布了新的文献求助10
4秒前
4秒前
5秒前
高挑的梦芝完成签到,获得积分10
5秒前
johnny发布了新的文献求助20
6秒前
6秒前
Trueman发布了新的文献求助10
7秒前
下山的虎完成签到 ,获得积分10
7秒前
7秒前
呜呼完成签到,获得积分10
8秒前
汉堡包应助CCCr采纳,获得10
8秒前
8秒前
Lunanar完成签到 ,获得积分10
8秒前
8秒前
wy发布了新的文献求助30
9秒前
张二十八发布了新的文献求助10
9秒前
znn发布了新的文献求助10
9秒前
所所应助予安采纳,获得10
10秒前
10秒前
10秒前
11秒前
量子星尘发布了新的文献求助100
11秒前
SciGPT应助要减肥含灵采纳,获得10
12秒前
12秒前
zhjeddie发布了新的文献求助10
12秒前
希望天下0贩的0应助Trueman采纳,获得10
13秒前
14秒前
高分求助中
Picture Books with Same-sex Parented Families: Unintentional Censorship 700
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
Effective Learning and Mental Wellbeing 300
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3974797
求助须知:如何正确求助?哪些是违规求助? 3519250
关于积分的说明 11197623
捐赠科研通 3255405
什么是DOI,文献DOI怎么找? 1797769
邀请新用户注册赠送积分活动 877156
科研通“疑难数据库(出版商)”最低求助积分说明 806202