Liposomal Delivery of an Immunostimulatory CpG Induces Robust Antitumor Immunity and Long‐Term Immune Memory by Reprogramming Tumor‐Associated Macrophages (Adv. Healthcare Mater. 6/2024)

重编程 免疫系统 纳米医学 免疫疗法 癌症研究 癌症免疫疗法 肿瘤微环境 医学 免疫学 化学 纳米技术 细胞 材料科学 生物化学 纳米颗粒
作者
Yujin Kim,Seojung Lee,Sangyong Jon
出处
期刊:Advanced Healthcare Materials [Wiley]
卷期号:13 (6)
标识
DOI:10.1002/adhm.202470042
摘要

Advanced Healthcare MaterialsVolume 13, Issue 6 2470042 Inside Back CoverFree Access Liposomal Delivery of an Immunostimulatory CpG Induces Robust Antitumor Immunity and Long-Term Immune Memory by Reprogramming Tumor-Associated Macrophages (Adv. Healthcare Mater. 6/2024) Yujin Kim, Yujin KimSearch for more papers by this authorSeojung Lee, Seojung LeeSearch for more papers by this authorSangyong Jon, Sangyong JonSearch for more papers by this author Yujin Kim, Yujin KimSearch for more papers by this authorSeojung Lee, Seojung LeeSearch for more papers by this authorSangyong Jon, Sangyong JonSearch for more papers by this author First published: 01 March 2024 https://doi.org/10.1002/adhm.202470042AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat Graphical Abstract Liposome-based Nanomedicine In article 2300549, Yujin Kim, Seojung Lee, and Sangyong Jon have developed a liposome-based nanomedicine that can polarize tumor-associated macrophages to proinflammatory M1-type macrophages. Liposomal delivery of an immune-stimulatory CpG via intratumoral injection could reshape the immunosuppressive tumor microenvironment, resulting in potent antitumor efficacy with long-term memory responses. This simple nanomedicine has the potential for use as a promising immunotherapeutic option applicable to a variety of tumors. Volume13, Issue6March 1, 20242470042 RelatedInformation

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