神经影像学
等级制度
静息状态功能磁共振成像
认知
生成语法
认知心理学
心理学
生成模型
大脑活动与冥想
神经科学
认知神经科学
神经功能成像
任务(项目管理)
自然主义
认知科学
计算机科学
人工智能
脑电图
认识论
哲学
经济
市场经济
管理
作者
Morten L. Kringelbach,Yonatan Sanz Perl,Enzo Tagliazucchi,Gustavo Deco
出处
期刊:Science Advances
[American Association for the Advancement of Science (AAAS)]
日期:2023-01-13
卷期号:9 (2)
被引量:46
标识
DOI:10.1126/sciadv.ade6049
摘要
Identifying the functional specialization of the brain has moved from using cognitive tasks and resting state to using ecological relevant, naturalistic movies. We leveraged a large-scale neuroimaging dataset to directly investigate the hierarchical reorganization of functional brain activity when watching naturalistic films compared to performing seven cognitive tasks and resting. A thermodynamics-inspired whole-brain model paradigm revealed the generative underlying mechanisms for changing the balance in causal interactions between brain regions in different conditions. Paradoxically, the hierarchy is flatter for movie-watching, and the level of nonreversibility is significantly smaller in comparison to both rest and tasks, where the latter in turn have the highest levels of hierarchy and nonreversibility. The underlying mechanisms were revealed by the model-based generative effective connectivity (GEC). Naturalistic films could therefore provide a fast and convenient way to measure important changes in GEC (integrating functional and anatomical connectivity) found in, for example, neuropsychiatric disorders. Overall, this study demonstrates the benefits of moving toward a more naturalistic neuroscience.
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