化学
芳基
组合化学
卤化物
可见光谱
电子受体
芳基
接受者
光化学
有机化学
材料科学
烷基
凝聚态物理
光电子学
物理
作者
Yutong Liu,Shuangqiao Li,Xueqin Chen,Hezhong Jiang
标识
DOI:10.1021/acs.joc.3c01201
摘要
We report an efficient radical-based and photocatalyst-free method for the C(sp2)–C(sp3) cross-coupling reaction to synthesize α-aryl ester derivatives. The process starts from a β-keto ester and an electron-deficient halogenated aryl halide under alkaline conditions to form an electron donor–acceptor complex and is driven by visible light. From the synthetic point of view, this newly established method represents a simple way to access arylpropionic acids from commercially available and cheap starting materials.
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