上睑下垂
工程伦理学
医学
工程类
免疫学
炎症
炎症体
作者
Rongchao Jin,X X Wang,F Liu,Huiying Rao
出处
期刊:PubMed
日期:2024-03-20
卷期号:32 (3): 284-288
标识
DOI:10.3760/cma.j.cn501113-20230115-00030
摘要
Pyroptosis is a newly discovered kind of cell death modality that, due to its association with innate immunity, plays a crucial role in cytolysis and inflammatory cytokine release during host defense against infection. In recent years, studies have shown that pyroptosis plays an important role in the occurrence and development of liver diseases. This article introduces and elaborates on the most recent research progress on pyroptosis in liver diseases based on the morphological features, molecular and pathophysiological mechanisms.细胞焦亡是一种新发现的细胞死亡形式。由于与固有免疫相关,焦亡在宿主抵抗感染时细胞溶解和炎症细胞因子释放方面起着至关重要的作用。近年来研究表明,细胞焦亡在肝病疾病的发生发展过程中起着重要作用。本文在介绍细胞焦亡的形态特征、分子和病理生理机制的基础上,着重阐述其在肝脏疾病中的最新研究进展。.
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