Fabrication and efficacy assessment of combination of brimonidine and ivermectin for treatment of papulopustular rosacea

Rosacea is a chronic inflammatory, multifactorial disease for which combination therapy could be an effective treatment. In this study, we evaluate the effect of the combination therapy of brimonidine 0.33% and ivermectin 1% as a single cream for the treatment of papulopustular rosacea.