神经氨酸酶
生物
飞道
病毒学
病毒
系统发育树
H5N1亚型流感病毒
H5N1基因结构
血凝素(流感)
禽流感病毒
甲型流感病毒
基因
遗传学
2019年冠状病毒病(COVID-19)
生态学
传染病(医学专业)
栖息地
病理
医学
疾病
作者
Wanjun Tang,X Li,Chen Hu,Chengshen Zhu,Z Li,Di Wu,T Wang,Guanghua He
出处
期刊:Acta Virologica
[AEPress, s.r.o.]
日期:2019-01-01
卷期号:63 (01): 121-125
被引量:4
摘要
The H8 subtype viruses are rarely isolated from wild ducks. Shanghai is one of the important wintering or stopover sites on the East Asia-Australia Migration Flyway. An influenza virus, subtype H8N4, was firstly isolated from a common teal (Anas crecca) in Shanghai during 2017-2018 in this study. To clarify the genetic characteristics of the H8N4 virus, the whole genome sequences were analyzed. Phylogenetic analysis of the hemagglutinin and neuraminidase genes showed that they shared highest nucleotide identity (99.19%-99.64%) with the Japan duck-origin H8N4 virus collected in 2016 (A/duck/Aichi/231003/2016) and belonged to the Eurasian-like avian lineage. Six other genes of the H8N4 isolated virus were all highly similar to the corresponding genes of a wide range of AIV subtypes including H9N2, H5N7, H3N8, H1N2, H4N6 and H1N1. The results indicated that the H8N4 virus was a multiple reassortant virus. The study emphasized that the continuous surveillance of influenza virus in wild birds should be strengthened. Keywords: avian influenza virus; H8N4; phylogenetic analysis; Shanghai.
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