New Clerodane Diterpenes from Tinospora sagittata var. yunnanensis

Four new clerodane diterpenes, namely sagittatayunnanosides A–D (1–4), were isolated from the roots of Tinospora sagittata var. yunnanensis, together with two known compounds, tinospinoside C (5) and tinospinoside E (6). The structures of the four new compounds were well elucidated by extensive analyses of the MS, IR, and 1D and 2D NMR data. The cytotoxic and antifouling activities of compounds 1–6 were evaluated.