Gastrointestinal bleeding in patients with Helicobacter pylori and dual platelet inhibition after myocardial infarction

In patients with ST-elevation myocardial infarction (STEMI) receiving dual antiplatelet therapy (DAPT), proton pump inhibitors are recommended for those at risk of upper gastrointestinal bleeding.1,2 The question of whether concurrent Helicobacter pylori infection increases the risk of upper gastrointestinal bleeding in this scenario is of major concern and has not been properly resolved.