Bi2WO6 has sparked a lot of attention as a gas sensor in recent years. However, in most cases, the working temperature is quite high. The Sn doped- Bi2WO6 slice-shaped nanostructure material was generated using a cost-effective one-step hydrothermal process in this study. The material was evaluated using X-ray diffraction (XRD), field emission scanning microscope (SEM), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), Brunauer-Emmett-Teller (BET) and an energy-dispersive X-ray detector (EDX). The results show that the 5 wt% Sn doped- Bi2WO6 sensor has outstanding isopropanol gas sensitivity. The sensor's optimal operating temperature is 260 °C, and it responds to low isopropanol concentrations. The unique interfacial interaction between 2D slice-shaped nanostructures and Sn doping, which provides additional catalytic active sites on the Bi2WO6 surface and improves electrical responsiveness and gas sensitivity, is responsible for the improved gas sensitivity.