姜黄素
生物利用度
痤疮
银屑病
药理学
皮肤癌
皮肤老化
多酚
医学
抗氧化剂
化学
癌症
皮肤病科
生物化学
内科学
作者
Yunes Panahi,Omid Fazlolahzadeh,Stephen L. Atkin,Muhammed Majeed,Alexandra E. Butler,Thomas P. Johnston,Amirhossein Sahebkar
摘要
Curcumin, a natural polyphenolic and yellow pigment obtained from the spice turmeric, has strong antioxidative, anti‐inflammatory, and antibacterial properties. Due to these properties, curcumin has been used as a remedy for the prevention and treatment of skin aging and disorders such as psoriasis, infection, acne, skin inflammation, and skin cancer. Curcumin has protective effects against skin damage caused by chronic ultraviolet B radiation. One of the challenges in maximizing the therapeutic potential of curcumin is its low bioavailability, limited aqueous solubility, and chemical instability. In this regard, the present review is focused on recent studies concerning the use of curcumin for the treatment of skin diseases, as well as offering new and efficient strategies to optimize its pharmacokinetic profile and increase its bioavailability.
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