糖尿病性视网膜病变
视网膜
医学
视网膜
炎症
下调和上调
平衡
眼底(子宫)
眼科
水肿
黄斑水肿
糖尿病
神经科学
内科学
内分泌学
生物
基因
生物化学
作者
Dongwei Lai,Yang Wu,Chuhan Shao,Qinghua Qiu
摘要
Diabetic macular edema (DME) is a common complication of diabetic retinopathy and is the leading cause of vision loss in diabetic patients. Various factors, such as metabolic disorders and inflammation caused by hyperglycemia, are involved in the occurrence and development of DME, but the specific mechanism is still unclear. Müller cells are a type of macroglial cell unique to the fundus, distributed throughout the retina, and they play a unique role in retinal homeostasis. This article reviews the role of Müller cells in the pathological process of DME and the research progress in the treatment of DME by targeting Müller cells through gene therapy.
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