抗菌剂
生物相容性
抗菌活性
化学
伤口愈合
生物传感器
检出限
生物医学工程
复合数
纳米技术
医学
材料科学
细菌
色谱法
外科
有机化学
生物
复合材料
冶金
遗传学
作者
Xiao Wang,Haoling Huo,Yanming Zhong,Yingfei Yang,Huaijun Lin,Lin Cao,Qiwei Wang,Congjie Xu,Zhidan Lin,Wei Li,Peng Zhang
标识
DOI:10.1002/adhm.202400580
摘要
High glucose blood and bacterial infection remain major issues for the slow healing of diabetic wounds, so developing functional biosensing composite with excellent antibacterial and remarkable glucose response sensitivity is necessary and prospective. Herein, by in situ synthesis AgNPs on the surface of self-prepared PTIGA elastomers, PTIGA-AgNPs conductive composites are obtained with efficient synergistic antibacterial effect, excellent mechanical and self-healing properties. The strain of the composites can reach 1800%, and its self-healing efficiency exceeds 90% at 60 °C within 8 h. Both elastomers and composites represent excellent biocompatibility and the antibacterial rate against E. coli and S. aureus exceeded 90%. Moreover, the biosensor assembled from the conductive composites exhibits excellent glucose response sensitivity and stability, with a sensitivity coefficient of 0.518 mA mm
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