非酒精性脂肪肝
医学
乙型肝炎病毒
乙型肝炎表面抗原
脂肪变性
乙型肝炎
肝病
内科学
脂肪肝
免疫学
疾病
纤维化
胃肠病学
病毒
病毒学
作者
Lili Liu,Hong Li,Yang Zhang,Jing Zhang,Zhenhuan Cao
出处
期刊:Heliyon
[Elsevier]
日期:2023-01-01
卷期号:9 (1): e13113-e13113
被引量:3
标识
DOI:10.1016/j.heliyon.2023.e13113
摘要
Hepatitis B virus (HBV) infection is still one kind of the infectious diseases that seriously threaten human health. Nonalcoholic fatty liver disease (NAFLD) has become the most common chronic liver disease worldwide. HBV infection complicated with NAFLD is increasingly common. This review mainly describes the interaction between HBV infection and NAFLD, the interaction between steatosis and antiviral drugs, and the prognosis of HBV infection complicated with NAFLD. Most studies suggest that HBV infection may reduce the incidence of NAFLD. NAFLD can promote the spontaneous clearance of hepatitis B surface antigen (HBsAg), but whether it affects antiviral efficacy has been reported inconsistently. HBV infection combined with NAFLD can promote the progression of liver fibrosis, especially in patients with severe steatosis. The outcome of HBV infection combined with NAFLD predisposing to the progression of HCC remains controversial.
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