光电流
化学
生物传感器
极性(国际关系)
光电子学
检出限
聚合物
光电化学
纳米技术
电极
材料科学
色谱法
电化学
有机化学
生物化学
物理化学
细胞
作者
Qingyuan Dong,Juan Xing,Ruo Yuan,Yali Yuan
出处
期刊:Analytical Chemistry
[American Chemical Society]
日期:2023-09-06
卷期号:95 (37): 13967-13974
被引量:13
标识
DOI:10.1021/acs.analchem.3c02548
摘要
Herein, we synthesized a novel porphyrinic covalent organic polymer (TPAPP-PTCA PCOP) for constructing a polarity-switchable dual-wavelength photoelectrochemical (PEC) biosensor with ferrocene (Fc) and hydrogen peroxide (H2O2) as regulator and amplifier simultaneously. Interestingly, this new PCOP possessed both n-type and p-type semiconductor characteristics, which thus enabled the appearance of a dual-polarity photocurrent at two different excitation wavelengths. Furthermore, Fc and H2O2 could readily switch the photocurrent of PCOP to the cathode and anode stemming from its efficient electron collection and donation function, respectively. Based on these, a PCOP-based PEC biosensor skillfully integrating dual wavelengths with reliable accuracy and polarity switch with high sensitivity was instituted. As a result, the developed PEC biosensor exhibited a low detection limit down to 0.089 pg mL-1 for the most powerful natural carcinogen aflatoxin M1 (AFM1) assay. Impressively, the target exhibited a completely opposite photocurrent difference to the interfering substances, and the linear correlation coefficient of the assay was improved compared to single-wavelength detection. The PEC sensing platform not only provided a basis for exploring multicharacteristic photoactive material but also innovatively developed the detection mode of the PEC biosensor.
科研通智能强力驱动
Strongly Powered by AbleSci AI