化学
紧身衣
荧光
红外线的
生物物理学
光化学
组合化学
光学
生物
物理
作者
Mohamed Bendellaa,Charlotte Cave,Amélie Godard,Fabien Dalonneau,Annika Sickinger,Christine Goze,Olivier Maury,Pierre Le Gendre,Ewen Bodio,Benoît Busser,Lucie Sancey
标识
DOI:10.1021/acs.jmedchem.4c01435
摘要
Aza-BODIPYs represent a class of fluorophores in which the π-conjugated system is rigidified and stabilized by a boron atom. A promising strategy to enhance their fluorescence properties involves replacing the boron atom with a metal ion. Here, we describe the synthesis and characterization of a water-soluble derivative where the metal is a gallium(III) ion, termed WazaGaY (water-soluble aza-GaDIPY). Water solubility is ensured by two ammonium substituents, inducing a bathochromic shift and a significant increase in quantum yield compared to that of the dimethylamino analog. The cellular behavior of
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