小檗碱
内皮干细胞
化学
癌症研究
细胞
药理学
泡沫电池
细胞生物学
医学
生物化学
生物
体外
胆固醇
脂蛋白
作者
Yang Hong,Jing Feng,Zijia Dou,Xiuxiu Sun,Yingying Hu,Zhouxiu Chen,Ling Liu,Henghui Xu,Menghan Du,Pingping Tang,Xin Liu,Yong Zhang
标识
DOI：10.1016/j.biopha.2024.117081
摘要
The discovery of an inhibitor for acyl-CoA synthetase long-chain family member 4 (ACSL4), a protein involved in the process of cell injury through ferroptosis, has the potential to ameliorate cell damage. In this study, we aimed to investigate the potential of berberine (BBR) as an inhibitor of ACSL4 in order to suppress endothelial ferroptosis and provide protection against atherosclerosis. An atherosclerosis model was created in ApoE
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