作者
Matthew F. Brown,Usa Reilly,J. A. Abramite,Joel T. Arcari,Robert M. Oliver,Rose A. Barham,Ye Che,Jinshan Michael Chen,Elizabeth M. Collantes,Seung Won Chung,Charlene Desbonnet,Jonathan L. Doty,Matthew Doroski,Juntyma J. Engtrakul,Thomas M. Harris,Michael D. Huband,John D. Knafels,Karen L. Leach,Shenping Liu,Anthony Marfat,Andrea Marra,Eric B. McElroy,Michael Melnick,Carol A. Menard,Justin I. Montgomery,Lisa Mullins,Mark C. Noe,John P. O’Donnell,Joseph Penzien,Mark S. Plummer,Loren Price,Veerabahu Shanmugasundaram,Christy L. Thoma,Daniel P. Uccello,Joseph S. Warmus,Donn G. Wishka
摘要
In this paper, we present the synthesis and SAR as well as selectivity, pharmacokinetic, and infection model data for representative analogues of a novel series of potent antibacterial LpxC inhibitors represented by hydroxamic acid 1a.
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iNk
36456657
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fillippo99
杳鸢
pcr163
tuanheqi
子车茗
丰知然
HCLonely
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