Detection of bone metastases in non‐small cell lung cancer patients: Comparison of whole‐body diffusion‐weighted imaging (DWI), whole‐body MR imaging without and with DWI, whole‐body FDG‐PET/CT, and bone scintigraphy

医学 骨闪烁照相术 核医学 磁共振成像 放射科 骨转移 全身成像 闪烁照相术 正电子发射断层摄影术 磁共振弥散成像 肺癌 接收机工作特性 转移 癌症 病理 内科学
作者
Daisuke Takenaka,Yoshiharu Ohno,Keiko Matsumoto,Nobukazu Aoyama,Yoshiaki Onishi,Hisanobu Koyama,Munenobu Nogami,Takeshi Yoshikawa,Shinsuke Matsumoto,Kazuro Sugimura
出处
期刊:Journal of Magnetic Resonance Imaging [Wiley]
卷期号:30 (2): 298-308 被引量:172
标识
DOI:10.1002/jmri.21858
摘要

To prospectively compare the capability for bone metastasis assessment of whole-body diffusion-weighted imaging (DWI), magnetic resonance imaging (MRI) without and with DWI, [(18)F] fluoro-2-D-glucose positron emission tomography with computed tomography (FDG-PET/CT) and bone scintigraphy in non-small cell carcinoma (NSCLC) patients.In all, 115 consecutive NSCLC patients (66 men, 49 women; mean age 72 years) prospectively underwent whole-body MRI, PET/CT, and bone scintigraphy before treatment. For each method, probability of metastasis was independently assessed by using a 5-point visual scoring system on a per-site basis. Receiver operating characteristic (ROC)-based positive tests were used to determine the practical threshold value for each method on a per-site basis. Sensitivities, specificities, and accuracies were then compared on a per-site and per-patient basis by means of McNemar's test.When the practical threshold values were adapted, specificity and accuracy of whole-body MRI with DWI were significantly higher than those of bone scintigraphy and PET/CT (P < 0.05). On a per-patient basis, specificity and accuracy of whole-body MRI with DWI were significantly higher than those of bone scintigraphy (P < 0.05).Whole-body MRI with DWI can be used for bone metastasis assessment of NSCLC patients as accurate as bone scintigraphy and/or PET/CT.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
momo发布了新的文献求助10
刚刚
刚刚
乐乐应助Mo采纳,获得10
1秒前
1秒前
Liufgui应助Z6kjoA采纳,获得20
1秒前
爆米花应助科研通管家采纳,获得10
3秒前
NexusExplorer应助科研通管家采纳,获得10
3秒前
cangy发布了新的文献求助10
3秒前
英姑应助科研通管家采纳,获得10
3秒前
地表飞猪应助科研通管家采纳,获得10
3秒前
桐桐应助科研通管家采纳,获得10
3秒前
4秒前
Akim应助科研通管家采纳,获得10
4秒前
Orange应助科研通管家采纳,获得10
4秒前
地表飞猪应助科研通管家采纳,获得10
4秒前
科研通AI2S应助科研通管家采纳,获得10
4秒前
酷波er应助科研通管家采纳,获得10
4秒前
地表飞猪应助科研通管家采纳,获得10
4秒前
4秒前
YamDaamCaa应助科研通管家采纳,获得30
4秒前
luo关闭了luo文献求助
5秒前
Jogging完成签到,获得积分10
6秒前
Villanellel发布了新的文献求助30
6秒前
李健应助ttt采纳,获得10
6秒前
科目三应助xueyu采纳,获得10
7秒前
Jello完成签到,获得积分10
10秒前
10秒前
111完成签到,获得积分10
11秒前
qq完成签到 ,获得积分10
11秒前
12秒前
hhhblabla应助ZZZ采纳,获得20
12秒前
12秒前
打打应助雨的痕迹采纳,获得10
14秒前
14秒前
好好发布了新的文献求助10
15秒前
西海岸的风完成签到 ,获得积分10
15秒前
TaoBijiang发布了新的文献求助10
17秒前
17秒前
18秒前
18秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
‘Unruly’ Children: Historical Fieldnotes and Learning Morality in a Taiwan Village (New Departures in Anthropology) 400
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3989334
求助须知:如何正确求助?哪些是违规求助? 3531428
关于积分的说明 11253936
捐赠科研通 3270119
什么是DOI,文献DOI怎么找? 1804887
邀请新用户注册赠送积分活动 882087
科研通“疑难数据库(出版商)”最低求助积分说明 809173