血脑屏障
抗体
医学
免疫学
神经科学
非人灵长类
中枢神经系统
双特异性抗体
生物
单克隆抗体
进化生物学
作者
Yang Yu,Jasvinder K. Atwal,Yin Zhang,Raymond K. Tong,Kristin R. Wildsmith,Christine Tan,Nga Bien‐Ly,Maria Hersom,Janice Maloney,William J. Meilandt,Daniela Bumbaca,Kapil Gadkar,Kwame Hoyte,Wilman Luk,Yanmei Lu,James A. Ernst,Kimberly Scearce‐Levie,Jessica A. Couch,Mark S. Dennis,Ryan J. Watts
出处
期刊：Science Translational Medicine
[American Association for the Advancement of Science (AAAS)]
日期：2014-11-05
卷期号：6 (261)
被引量：302
标识
DOI：10.1126/scitranslmed.3009835
摘要
Bispecific antibodies engineered to both bind to the primate transferrin receptor and inhibit β-secretase are taken up by the nonhuman primate brain and reduce brain β-amyloid.
科研通智能强力驱动
Strongly Powered by AbleSci AI
杳鸢
Endlessway
一一
xjcy
不配.
汀烟
劲秉
8R60d8
嗯哼
子车茗
坚强的广山
ephore
彭于彦祖
36456657
好困
HEIKU
tuanheqi
lalala
寻道图强
Henry
皖公网安备34019202002308
