奥克列珠单抗
医学
干扰素β-1a
多发性硬化
危险系数
内科学
置信区间
胃肠病学
免疫学
干扰素β
美罗华
淋巴瘤
作者
Stephen L. Hauser,Amit Bar‐Or,Gıancarlo Comı,Gavin Giovannoni,Hans‐Peter Hartung,Bernhard Hemmer,Fred Lublin,Xavier Montalbán,Kottil Rammohan,Krzysztof Selmaj,Anthony Traboulsee,Jerry S. Wolinsky,Douglas L. Arnold,Gaëlle Klingelschmitt,Donna Masterman,Paulo Fontoura,Shibeshih Belachew,Peter Chin,Nicole Mairon,Hideki Garren,Ludwig Kappos
标识
DOI:10.1056/nejmoa1601277
摘要
B cells influence the pathogenesis of multiple sclerosis. Ocrelizumab is a humanized monoclonal antibody that selectively depletes CD20+ B cells.
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