化学
部分
腙
吡啶
抗真菌
微波辐射
生物活性
三氟甲基
组合化学
立体化学
有机化学
生物化学
体外
催化作用
微生物学
生物
烷基
作者
Min Liu,Yanhong Shi,Ming‐Yan Yang,Zhi‐Wen Zhai,Jian‐Quan Weng,Cheng‐Xia Tan,Xinghai Liu,Baoju Li,Yonggang Zhang
出处
期刊:Letters in Drug Design & Discovery
[Bentham Science]
日期:2016-03-03
卷期号:13 (4): 324-328
被引量:4
标识
DOI:10.2174/1570180812666151003002140
摘要
A series of novel hydrazone derivatives containing pyridine moiety were designed and synthesized from 2,3-dichloro-5-(trifluoromethyl)pyridine as starting materials under microwave irradiation, and their structures were characterized by 1H NMR, MS and elemental analysis. The biological activity of title compounds was determined. The results indicated that some of title compounds exhibited good antifungal activity. Keywords: Hydrazone, pyridine, microwave assistant synthesis, antifungal activity.
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