Antibacterial Agents: Vacancy‐Induced Antibacterial Activity of XS 2– y Quantum Dots against Drug‐Resistant Bacteria for Treatment of Bacterial Keratitis (Small 42/2020)

SmallVolume 16, Issue 42 2070230 Inside Front CoverFree Access Antibacterial Agents: Vacancy-Induced Antibacterial Activity of XS2–y Quantum Dots against Drug-Resistant Bacteria for Treatment of Bacterial Keratitis (Small 42/2020) Huiyuan Li, Huiyuan Li Department of Ophthalmology, Jinan Central Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012 ChinaSearch for more papers by this authorXiao Wang, Xiao Wang Medical Laboratory Diagnosis Center, Jinan Central Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250013 ChinaSearch for more papers by this authorXiaofei Zhao, Xiaofei Zhao Department of Ophthalmology, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250033 ChinaSearch for more papers by this authorGuanhua Li, Guanhua Li Department of Respiratory and Critical Care Medicine, Jinan Central Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250013 ChinaSearch for more papers by this authorFengyan Pei, Fengyan Pei Medical Laboratory Diagnosis Center, Jinan Central Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250013 ChinaSearch for more papers by this authorHan Zhang, Han Zhang Department of Ophthalmology, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250033 ChinaSearch for more papers by this authorYang Tan, Yang Tan School of Physics, State Key Laboratory of Crystal Materials, Shandong University, Jinan, Shandong, 250100 ChinaSearch for more papers by this authorFeng Chen, Feng Chen School of Physics, State Key Laboratory of Crystal Materials, Shandong University, Jinan, Shandong, 250100 ChinaSearch for more papers by this author Huiyuan Li, Huiyuan Li Department of Ophthalmology, Jinan Central Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012 ChinaSearch for more papers by this authorXiao Wang, Xiao Wang Medical Laboratory Diagnosis Center, Jinan Central Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250013 ChinaSearch for more papers by this authorXiaofei Zhao, Xiaofei Zhao Department of Ophthalmology, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250033 ChinaSearch for more papers by this authorGuanhua Li, Guanhua Li Department of Respiratory and Critical Care Medicine, Jinan Central Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250013 ChinaSearch for more papers by this authorFengyan Pei, Fengyan Pei Medical Laboratory Diagnosis Center, Jinan Central Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250013 ChinaSearch for more papers by this authorHan Zhang, Han Zhang Department of Ophthalmology, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250033 ChinaSearch for more papers by this authorYang Tan, Yang Tan School of Physics, State Key Laboratory of Crystal Materials, Shandong University, Jinan, Shandong, 250100 ChinaSearch for more papers by this authorFeng Chen, Feng Chen School of Physics, State Key Laboratory of Crystal Materials, Shandong University, Jinan, Shandong, 250100 ChinaSearch for more papers by this author First published: 22 October 2020 https://doi.org/10.1002/smll.202070230AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Graphical Abstract In article number 2004677, Han Zhang, Yang Tan, Feng Chen, and co-workers demonstrate that the antibacterial ability against drug-resistant bacteria can be endowed to transition metal dichalcogenides (XS2, X = Mo/W) quantum dots by sulfur vacancies, and their application in bacterial keratitis. The sulfur vacancies generated by the ion irradiation result in the one-way electron transport from the external environment to XS2, leading to a strong ROS-independent oxidative stress. For biomedical application against bacterial keratitis, it is observed that the occurrence of severe clinical manifestation like ocular perforation can be prevented. Volume16, Issue42October 22, 20202070230 RelatedInformation