医学
危险系数
维生素B12
肥胖
体质指数
同型半胱氨酸
比例危险模型
全国健康与营养检查调查
人口
维生素
生理学
死因
内科学
入射(几何)
疾病
环境卫生
置信区间
物理
光学
作者
Xiao Wang,Hongxia Peng,Congying Xia,Qinghua Zhou,Liqing Shen,Xinran Cheng,Chunxia Yang,Yanfang Yang,Lü Long
出处
期刊:Nutrition
[Elsevier]
日期:2023-12-01
卷期号:116: 112189-112189
被引量:3
标识
DOI:10.1016/j.nut.2023.112189
摘要
Future primary prevention strategies may benefit from understanding the connection between mortality in individuals with central obesity and modifiable lifestyle factors like dietary intake. This study sought to determine whether there was a separate relationship between folate, vitamin B6, and vitamin B12 intake and all-cause and cause-specific mortality in the US population with central obesity.The study analyzed data from the National Health and Nutrition Examination Survey between 1999 and 2016. Using the Cox proportional hazards model, the association between dietary intake of B vitamins and all-cause and cause-specific mortality was examined. A total of 7718 adults with central obesity were enrolled, with a mean age of 49.87 (SD = 0.25) y at baseline.Folate intake was independently associated with a decreased incidence of all-cause mortality (adjusted hazard ratio = 0.71; 95% CI, 0.58-0.87). Furthermore, higher intake of vitamin B6 and vitamin B12 was inversely correlated with cardiovascular disease mortality (adjusted hazard ratio = 0.63; 95% CI, 0.40-0.98; and adjusted hazard ratio = 0.44; 95% CI, 0.29-0.65, respectively) and the finding reveal an interaction between homocysteine and vitamin B12 and folate on All-cause mortality CONCLUSIONS: The findings of this study suggest that vitamin B12 and folate intake may be protective factors in individuals with central obesity. It is important to consider both their total homocysteine level and body mass index in conjunction with these nutrients. Further research is needed to validate these findings.
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