Reaffirmation of Mechanistic Proteomic Signatures Accompanying SGLT2 Inhibition in Patients With Heart Failure
医学
心力衰竭
心脏病学
内科学
药理学
作者
Milton Packer,João Pedro Ferreira,Javed Butler,Jingmei Li,James L. Januzzi,Sandra González Maldonado,Marina Panova‐Noeva,Stuart J. Pocock,Jürgen H. Prochaska,Maral Saadati,Naveed Sattar,Mikhail Sumin,Stefan D. Anker,Faı̈ez Zannad
Sodium-glucose cotransporter 2 (SGLT2) inhibitors exert a distinctive pattern of direct biological effects on the heart and kidney under experimental conditions, but the meaningfulness of these signatures for patients with heart failure has not been fully defined.