Microbial Production of Amines and Amino Acids by Fermentation

Amino acids and derived amines are widely produced and utilized industrially. Fermentation is the preferred route for amino acid production. Established fermentation processes are characterized by economies of scale. Therefore, producing strains are constantly improved with regard to titer, yield, and productivity as key performance indicators embracing the newest metabolic engineering technologies. Furthermore, metabolic engineering enabled the production of non-proteinogenic amino acids, omega-amino acids, functionalized amino acids, and diamines. In this chapter, we will focus on strain development for the fermentative production of these nitrogenous compounds by bacteria.