Association of human leukocyte antigen with IgA vasculitis with nephritis in Japanese children

Pediatrics InternationalVolume 65, Issue 1 e15422 CLINICAL NOTE Association of human leukocyte antigen with IgA vasculitis with nephritis in Japanese children Tomohiko Nishino, Corresponding Author Tomohiko Nishino [email protected] orcid.org/0000-0003-4287-979X Department of Pediatrics, Teikyo University School of Medicine, Tokyo, Japan Correspondence Tomohiko Nishino, Department of Pediatrics, Teikyo University School of Medicine, 2-11-1, Kaga, Itabashi-ku, Tokyo 173-8605, Japan. Email: [email protected]Search for more papers by this authorKazuhiro Takahashi, Kazuhiro Takahashi Department of Pediatrics, Teikyo University School of Medicine, Tokyo, JapanSearch for more papers by this authorShinya Tomori, Shinya Tomori orcid.org/0000-0002-9475-8327 Department of Pediatrics, Teikyo University School of Medicine, Tokyo, JapanSearch for more papers by this authorSayaka Ono, Sayaka Ono orcid.org/0000-0002-3771-5005 Department of Pediatrics, Teikyo University School of Medicine, Tokyo, JapanSearch for more papers by this authorMasakazu Mimaki, Masakazu Mimaki Department of Pediatrics, Teikyo University School of Medicine, Tokyo, JapanSearch for more papers by this author Tomohiko Nishino, Corresponding Author Tomohiko Nishino [email protected] orcid.org/0000-0003-4287-979X Department of Pediatrics, Teikyo University School of Medicine, Tokyo, Japan Correspondence Tomohiko Nishino, Department of Pediatrics, Teikyo University School of Medicine, 2-11-1, Kaga, Itabashi-ku, Tokyo 173-8605, Japan. Email: [email protected]Search for more papers by this authorKazuhiro Takahashi, Kazuhiro Takahashi Department of Pediatrics, Teikyo University School of Medicine, Tokyo, JapanSearch for more papers by this authorShinya Tomori, Shinya Tomori orcid.org/0000-0002-9475-8327 Department of Pediatrics, Teikyo University School of Medicine, Tokyo, JapanSearch for more papers by this authorSayaka Ono, Sayaka Ono orcid.org/0000-0002-3771-5005 Department of Pediatrics, Teikyo University School of Medicine, Tokyo, JapanSearch for more papers by this authorMasakazu Mimaki, Masakazu Mimaki Department of Pediatrics, Teikyo University School of Medicine, Tokyo, JapanSearch for more papers by this author First published: 22 November 2022 https://doi.org/10.1111/ped.15422Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat No abstract is available for this article. CONFLICT OF INTEREST The authors declare no conflict of interest. Open Research DATA AVAILABILITY STATEMENT The datasets generated and analyzed during the current study are available from the corresponding author upon reasonable request. Supporting Information Filename Description ped15422-sup-0001-TableS1.docxWord 2007 document , 37.4 KB Table S1 Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article. REFERENCES 1Robson KJ, Ooi JD, Holdsworth SR, Rossjohn J, Kitching AR. HLA and kidney disease: from associations to mechanisms. Nat Rev Nephrol. 2018; 14: 636–55. 2Koskela M, Nihtila J, Ylinen E, Kolho KL, Nuutinen M, Ritari J, et al. HLA-DQ and HLA-DRB1 alleles associated with Henoch-Schonlein purpura nephritis in Finnish pediatric population: a genome-wide association study. Pediatr Nephrol. 2021; 36: 2311–8. 3Hastings MC, Rizk DV, Kiryluk K, Nelson R, Zahr RS, Novak J, et al. IgA vasculitis with nephritis: update of pathogenesis with clinical implications. Pediatr Nephrol. 2022; 37: 719–33. 4Gardner-Medwin JM, Dolezalova P, Cummins C, Southwood TR. Incidence of Henoch-Schonlein purpura, Kawasaki disease, and rare vasculitides in children of different ethnic origins. Lancet. 2002; 360: 1197–202. 5Jauhola O, Ronkainen J, Koskimies O, Ala-Houhala M, Arikoski P, Holtta T, et al. Renal manifestations of Henoch-Schonlein purpura in a 6-month prospective study of 223 children. Arch Dis Child. 2010; 95: 877–82. 6 HLA Laboratory [homepage on the internet]. Kyoto: Allele Frequency and Serotype Frequency, Public Interest Incorporated Foundation HLA RABORATORY. [cited 2022 Oct 16]. Available from: https://hla.or.jp/med/frequency_search/en/allele/ and https://hla.or.jp/med/frequency_search/en/sero/ 7Feehally J, Farrall M, Boland A, Gale DP, Gut I, Heath S, et al. HLA has strongest association with IgA nephropathy in genome-wide analysis. J Am Soc Nephrol. 2010; 21: 1791–7. Volume65, Issue1January/December 2023e15422 ReferencesRelatedInformation