怀孕
蜕膜
子宫内膜
胚泡
胚胎
胎盘
胎儿
医学
生物
产科
胚胎发生
遗传学
作者
Inmaculada Moreno,Antonio Capalbo,Aymara Mas,Tamara Garrido‐Gómez,Beatriz Rosón,Maurizio Poli,Eva Dimitriadis,Xavier Alegre Santamaría,Felipe Vilella,Carlos Simón
标识
DOI:10.1152/physrev.00050.2021
摘要
Pregnancy is established during the periconceptional period as a continuum beginning with blastocyst attachment to the endometrial epithelial surface followed by embryo invasion and placenta formation. This period sets the foundation for the child and mother’s health during pregnancy. Emerging evidence indicates that prevention of downstream pathologies in both the embryo/newborn and pregnant mother may be possible at this stage. In this review, we discuss current advances in the periconceptional space, including the preimplantation human embryo and maternal endometrium. We also discuss the role of the maternal decidua, the periconceptional maternal-embryonic interface, the dialogue between these elements, and the importance of the endometrial microbiome in the implantation process and pregnancy. Finally, we discuss the myometrium in the periconceptional space and review its role in determining pregnancy health.
科研通智能强力驱动
Strongly Powered by AbleSci AI