Cutaneous blisters mimicking bullous pemphigoid

A 70-year-old man presented at Binzhou Medical University Hospital (Shandong, China) with a 2-month history of pruritic blisters. He had initially been diagnosed with bullous pemphigoid in September, 2022, but his skin blistering worsened despite symptomatic treatment. Upon cutaneous examination, multiple blisters, erosions, ulcerations, and scabs were observed on his trunk, hands, and feet (figure). A skin biopsy of the right hand revealed subepidermal blisters, along with an infiltration of eosinophils and lymphocytes around blood vessels in the superficial middle dermis.