Systematic rare variant analyses identify RAB32 as a susceptibility gene for familial Parkinson’s disease
生物
帕金森病
遗传学
疾病
基因
内科学
医学
作者
Paul J. Hop,Dongbing Lai,Pamela Keagle,Desiree M. Baron,Brendan Kenna,Maarten Kooyman,Shankaracharya,Cheryl Halter,Letizia Straniero,Rosanna Asselta,Salvatore Bonvegna,Alexandra I. Soto‐Beasley,Zbigniew K. Wszołek,Ryan J. Uitti,Ioannis U. Isaias,Gianni Pezzoli,Nicola Ticozzi,Owen A. Ross,Jan H. Veldink,Tatiana Foroud,Kevin P. Kenna,John E. Landers
Despite substantial progress, causal variants are identified only for a minority of familial Parkinson's disease (PD) cases, leaving high-risk pathogenic variants unidentified