Rates of Vascular Occlusion Associated With Using Needles vs Cannulas for Filler Injection

医学 闭塞 血管闭塞 套管 血管闭合器 外科 填料(材料) 止血 材料科学 复合材料
作者
Murad Alam,Rohit Kakar,Jeffrey S. Dover,Vishnu Harikumar,Bianca Y. Kang,Hoi Ting Wan,Emily Poon,Derek Jones
出处
期刊:JAMA Dermatology [American Medical Association]
卷期号:157 (2): 174-174 被引量:55
标识
DOI:10.1001/jamadermatol.2020.5102
摘要

Importance

Soft-tissue augmentation with skin fillers can be delivered with needles or microcannulas, but unwanted vascular occlusions are possible.

Objective

To determine whether filler-associated vascular occlusion events of the face occur more often with injections performed with needles than with microcannulas.

Design, Setting, and Participants

This retrospective cohort study included a random sample of board-certified dermatologists deemed eligible based on membership in relevant professional societies and attendance at relevant national professional meetings. Participants completed detailed forms in which they could enter deidentified data and volume statistics pertaining to patients undergoing filler procedures in their practices. Data were collected from August 2018 to August 2019.

Exposures

Injectable fillers approved by the US Food and Drug Administration delivered via needles or microcannulas.

Main Outcomes and Measures

The primary outcome measure was intravascular occlusion. Occlusion events were graded by severity (no sequelae, scar, and ocular injury or blindness).

Results

A total of 370 dermatologists (mean [SD] years in practice, 22.3 [11.1] years) participated and reported 1.7 million syringes injected. The risk of occlusion with any particular filler type using needle or cannula never exceeded 1 per 5000 syringes injected. Overall, 1 occlusion per 6410 per 1-mL syringe injections was observed with needles and 1 per 40 882 with cannulas (P < .001). Of the 370 participants, 106 (28.6%) reported at least 1 occlusion. Multivariate analysis found that injections with cannula had 77.1% lower odds of occlusion compared with needle injections. Participants injecting fillers for more than 5 years had 70.7% lower odds of occlusion than those who were less experienced. For each additional injection per week, the odds of occlusion decreased by 1%, and 85% of occlusions had no long-term sequelae. Nasolabial folds and lips were most likely to be occluded, with mean severity level of occlusions highest at the glabella.

Conclusions and Relevance

In this cohort study, filler injections with either needles or cannulas were associated with a very low risk of intravascular occlusion events. Moreover, the vast majority of such events were minor and resolved without scar or other injury. Injections with microcannulas were less often associated with occlusion events than injections with needles. Occlusion risk per syringe appeared decreased after the first few years of clinical practice and was also lower among those who more frequently inject fillers. Whether a needle or cannula is most appropriate for injection may depend on patient factors, anatomic site, and the type of defect being treated.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
念所三旬发布了新的文献求助10
1秒前
奶糖爱果冻完成签到 ,获得积分10
2秒前
大唐元给大唐元的求助进行了留言
3秒前
优秀沛春发布了新的文献求助10
3秒前
研友_pnx7JL发布了新的文献求助10
3秒前
今天你读文献了吗完成签到,获得积分10
4秒前
4秒前
5秒前
concise完成签到 ,获得积分10
5秒前
6秒前
hhh完成签到 ,获得积分10
7秒前
量子星尘发布了新的文献求助10
7秒前
畅快从云完成签到 ,获得积分10
7秒前
7秒前
7秒前
田様应助周而复始@采纳,获得10
7秒前
羲合发布了新的文献求助10
8秒前
keep完成签到 ,获得积分10
8秒前
9秒前
研友_pnx7JL完成签到,获得积分10
9秒前
10秒前
10秒前
10秒前
TYT发布了新的文献求助10
10秒前
CR发布了新的文献求助10
11秒前
潇潇鱼发布了新的文献求助10
11秒前
18746005898完成签到 ,获得积分10
11秒前
11秒前
11秒前
11秒前
11秒前
快乐秋玲发布了新的文献求助30
12秒前
12秒前
12秒前
FashionBoy应助cheersyu采纳,获得10
12秒前
12秒前
12秒前
12秒前
12秒前
12秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Cognitive Neuroscience: The Biology of the Mind 1000
Technical Brochure TB 814: LPIT applications in HV gas insulated switchgear 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Picture Books with Same-sex Parented Families: Unintentional Censorship 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3969557
求助须知:如何正确求助?哪些是违规求助? 3514377
关于积分的说明 11173836
捐赠科研通 3249692
什么是DOI,文献DOI怎么找? 1794979
邀请新用户注册赠送积分活动 875537
科研通“疑难数据库(出版商)”最低求助积分说明 804836