已入深夜,您辛苦了!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!祝你早点完成任务,早点休息,好梦!

Rates of Vascular Occlusion Associated With Using Needles vs Cannulas for Filler Injection

医学 闭塞 血管闭塞 套管 血管闭合器 外科 填料(材料) 止血 材料科学 复合材料
作者
Murad Alam,Rohit Kakar,Jeffrey S. Dover,Vishnu Harikumar,Bianca Y. Kang,Hoi Ting Wan,Emily Poon,Derek Jones
出处
期刊:JAMA Dermatology [American Medical Association]
卷期号:157 (2): 174-174 被引量:55
标识
DOI:10.1001/jamadermatol.2020.5102
摘要

Importance

Soft-tissue augmentation with skin fillers can be delivered with needles or microcannulas, but unwanted vascular occlusions are possible.

Objective

To determine whether filler-associated vascular occlusion events of the face occur more often with injections performed with needles than with microcannulas.

Design, Setting, and Participants

This retrospective cohort study included a random sample of board-certified dermatologists deemed eligible based on membership in relevant professional societies and attendance at relevant national professional meetings. Participants completed detailed forms in which they could enter deidentified data and volume statistics pertaining to patients undergoing filler procedures in their practices. Data were collected from August 2018 to August 2019.

Exposures

Injectable fillers approved by the US Food and Drug Administration delivered via needles or microcannulas.

Main Outcomes and Measures

The primary outcome measure was intravascular occlusion. Occlusion events were graded by severity (no sequelae, scar, and ocular injury or blindness).

Results

A total of 370 dermatologists (mean [SD] years in practice, 22.3 [11.1] years) participated and reported 1.7 million syringes injected. The risk of occlusion with any particular filler type using needle or cannula never exceeded 1 per 5000 syringes injected. Overall, 1 occlusion per 6410 per 1-mL syringe injections was observed with needles and 1 per 40 882 with cannulas (P < .001). Of the 370 participants, 106 (28.6%) reported at least 1 occlusion. Multivariate analysis found that injections with cannula had 77.1% lower odds of occlusion compared with needle injections. Participants injecting fillers for more than 5 years had 70.7% lower odds of occlusion than those who were less experienced. For each additional injection per week, the odds of occlusion decreased by 1%, and 85% of occlusions had no long-term sequelae. Nasolabial folds and lips were most likely to be occluded, with mean severity level of occlusions highest at the glabella.

Conclusions and Relevance

In this cohort study, filler injections with either needles or cannulas were associated with a very low risk of intravascular occlusion events. Moreover, the vast majority of such events were minor and resolved without scar or other injury. Injections with microcannulas were less often associated with occlusion events than injections with needles. Occlusion risk per syringe appeared decreased after the first few years of clinical practice and was also lower among those who more frequently inject fillers. Whether a needle or cannula is most appropriate for injection may depend on patient factors, anatomic site, and the type of defect being treated.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
Akim应助tjh采纳,获得10
刚刚
xia完成签到,获得积分10
1秒前
Singularity应助墨菲特采纳,获得10
2秒前
王一生完成签到,获得积分0
2秒前
song发布了新的文献求助10
2秒前
yu完成签到 ,获得积分10
4秒前
6秒前
halo完成签到 ,获得积分10
6秒前
7秒前
8秒前
白熊完成签到,获得积分10
8秒前
ruaruaburua发布了新的文献求助10
9秒前
踏实的傲白完成签到 ,获得积分10
10秒前
guozizi发布了新的文献求助10
11秒前
14秒前
生活的狗完成签到,获得积分10
15秒前
安内大大完成签到,获得积分20
17秒前
Akim应助自然的汉堡采纳,获得10
19秒前
ZhX发布了新的文献求助60
19秒前
安内大大发布了新的文献求助10
19秒前
李爱国应助小田采纳,获得10
20秒前
20秒前
20秒前
22秒前
鳗鱼冰薇完成签到 ,获得积分10
23秒前
23秒前
年轻的雁露完成签到,获得积分10
23秒前
皮老师发布了新的文献求助10
25秒前
桐桐应助mashichuang采纳,获得10
25秒前
26秒前
科研通AI5应助粉条采纳,获得10
26秒前
桑叶发布了新的文献求助10
27秒前
cAMP关注了科研通微信公众号
28秒前
leisure完成签到,获得积分20
29秒前
皮老师完成签到,获得积分10
30秒前
旅顺口老李完成签到 ,获得积分10
31秒前
希望天下0贩的0应助ta采纳,获得10
32秒前
上官若男应助song采纳,获得10
33秒前
33秒前
冷水发布了新的文献求助10
36秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 700
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3976418
求助须知:如何正确求助?哪些是违规求助? 3520512
关于积分的说明 11203586
捐赠科研通 3257127
什么是DOI,文献DOI怎么找? 1798594
邀请新用户注册赠送积分活动 877804
科研通“疑难数据库(出版商)”最低求助积分说明 806523