医学
内科学
急性冠脉综合征
弗雷明翰风险评分
预测值
胃肠病学
心脏病学
心肌梗塞
疾病
作者
S. Demirtas,Hamza Sunman,Ayşe Nur Özkaya İbiş,Muhammed Erzurum,Nail Burak Özbeyaz,Engin Algül,Yasemin Gündüz,Hilal Erken Pamukçu,Kadriye Gayretli,Haluk Furkan Şahan
出处
期刊:Kardiologiya
[APO Society of Specialists in Heart Failure]
日期:2021-02-11
卷期号:61 (1): 59-65
被引量:7
标识
DOI:10.18087/cardio.2021.1.n1254
摘要
Objective The importance of nutritional status in non-ST segment elevated acute coronary syndrome (NSTE-ACS) is not clear. In this study, the importance of prognostic nutritional index (PNI) in terms of in-hospital mortality in patients with NSTE-ACS and its relationship with the Global Record of Acute Coronary Events (GRACE) risk score were investigated. Material and methods A total of 498 consecutive NSTE-ACS patients were recorded retrospectively. PNI for nutritional status assessment of patients with NSTE-ACS. PNI was calculated as 10 × serum albumin (g / dL) + 0.005 × total lymphocyte count (per mm3). The association between PNI and GRACE risk score was assessed. Results Patients were classified as low-risk group (≤108 points, n=222), medium-risk group (109–140 points, n=161) and high-risk group (>140 points, n=115) according to the GRACE score. The mean PNI value was found to be the lowest in the high-risk group compared to other risk groups. There was a significant negative correlation between GRACE risk score and PNI (p<0.001). In multivariate analysis, PNI resulted as a predictor of in-hospital mortality independent of GRACE risk score (OR=0.909; 95 % CI: 0.842–0.981; p=0.01). PNI value in the high risk group for in-hospital mortality was determined to have significant predictive ability (AUC=0.710; 95 % CI: 0.61–0.80; p<0001). Conclusions PNI evaluation is a useful and easy method to evaluate the nutritional status of patients with NSTE-ACS. Our study suggests that the PNI is significantly associated with in-hospital mortality, and GRACE risk score in patients with NSTE-ACS. This study is the basis for new studies to investigate whether PNI contributes additional prognostic to the GRACE risk score.
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