致盲
安慰剂
医学
心理干预
随机对照试验
临床试验
替代医学
物理疗法
心理学
精神科
外科
内科学
病理
作者
Rebecca Webster,Felicity L. Bishop,Gary S. Collins,Andrea W.M. Evers,Tammy Hoffmann,J. André Knottnerus,Sarah E Lamb,Helen Macdonald,Claire Madigan,Vitaly Napadow,Amy Price,Jonathan Rees,Jeremy Howick
标识
DOI:10.1016/j.jclinepi.2021.02.022
摘要
'Blinding' involves concealing knowledge of which trial participants received the interventions from participants themselves and other trial personnel throughout the trial. Blinding reduces bias arising from the beliefs and expectations of these groups. It is agreed that where possible, blinding should be attempted, for example by ensuring that experimental and control treatments look the same. However, there is a debate about if we should measure whether blinding has been successful, this manuscript will discuss this controversy, including the benefits and risks of measuring blinding within the randomised controlled trial.
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