分解代谢抑制
胆固醇
肥胖
体重
生物
内分泌学
内科学
药理学
生物化学
医学
基因
突变体
出处
期刊:Journal of Nutritional Science and Vitaminology
[Center for Academic Publications Japan]
日期:1993-01-01
卷期号:39 (5): 537-543
被引量:28
摘要
An anti-obesity effect was observed for cholest-4-en-3-one (cholestenone) which is an intestinal catabolite of cholesterol. Body weight gain and body fat accumulation of CDF 1 mice were inhibited by 0.5% dietary exposure to this chemical. Dose response for the effect of cholestenone was found to increase as the dose rose from 0.1 to 0.3% and 0.500. No obvious anomaly due to consumption of cholestenone was detected by necropsy and clinical observation. The mechanism of this effect of cholestenone is not known at present, but it was not due to anorexia.
科研通智能强力驱动
Strongly Powered by AbleSci AI