Development of a Nomogram for Prediction of Vaginal Birth After Cesarean Delivery

列线图 医学 逻辑回归 独生子女 产科 剖宫产 阴道分娩 阴道分娩 妊娠期 怀孕 遗传学 生物 内科学
作者
William A. Grobman,Yinglei Lai,Mark B. Landon,Catherine Y. Spong,Kenneth J. Leveno,Dwight J. Rouse,Michael W. Varner,Atef H. Moawad,Steve N. Caritis,Margaret Harper,Ronald J. Wapner,Yoram Sorokin,Menachem Miodovnik,Marshall Carpenter,Mary J. OʼSullivan,Baha M. Sibai,Oded Langer,John M. Thorp,Susan M. Ramin,Brian M. Mercer
出处
期刊:Obstetrics & Gynecology [Lippincott Williams & Wilkins]
卷期号:109 (4): 806-812 被引量:450
标识
DOI:10.1097/01.aog.0000259312.36053.02
摘要

In Brief OBJECTIVE: To develop a model based on factors available at the first prenatal visit that predicts chance of successful vaginal birth after cesarean delivery (VBAC) for individual patients who undergo a trial of labor. METHODS: All women with one prior low transverse cesarean who underwent a trial of labor at term with a vertex singleton gestation were identified from a concurrently collected database of deliveries at 19 academic centers during a 4-year period. Using factors identifiable at the first prenatal visit, we analyzed different classification techniques in an effort to develop a meaningful prediction model for VBAC success. After development and cross-validation, this model was represented by a graphic nomogram. RESULTS: Seven-thousand six hundred sixty women were available for analysis. The prediction model is based on a multivariable logistic regression, including the variables of maternal age, body mass index, ethnicity, prior vaginal delivery, the occurrence of a VBAC, and a potentially recurrent indication for the cesarean delivery. After analyzing the model with cross-validation techniques, it was found to be both accurate and discriminating. CONCLUSION: A predictive nomogram, which incorporates six variables easily ascertainable at the first prenatal visit, has been developed that allows the determination of a patient-specific chance for successful VBAC for those women who undertake trial of labor. LEVEL OF EVIDENCE: II Using six patient characteristics easily ascertainable at the first prenatal visit, we have developed a model for prediction of vaginal birth after cesarean for women who undergo a trial of labor.
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