Gene Expression Profiling of Cells, Tissues, and Developmental Stages of the Nematode C. elegans

Completion of the DNA sequences of the humangenome and that of the nematode Caenorhabditis elegansallows the large-scale identification and analysis of orthologs of human genes in an organism amenable to detailed genetic and molecular analyses. We are determining gene expression profiles in specific cells, tissues, anddevelopmental stages in C. elegans. Our ultimate goal isnot only to describe detailed gene expression profiles, butalso to gain a greater understanding of the organization ofgene regulatory networks and to determine how they control cell function during development and differentiation...