自愈水凝胶
材料科学
组分(热力学)
细胞外基质
细胞外
基质(化学分析)
海藻酸钙
纳米技术
生物物理学
钙
复合材料
高分子化学
化学
生物化学
生物
热力学
物理
冶金
作者
Brian M. Gillette,Jacob A. Jensen,Meixin Wang,Jason Tchao,Samuel K. Sia
标识
DOI:10.1002/adma.200902265
摘要
This article describes fabrication of a two-component extracellular matrix (ECM) in which one component acts as a stable structural element and another component gels or dissolves reversibly (a modulatory component). Using a composite collagen-alginate ECM, reversible crosslinking of the alginate (the modulatory component) via application of calcium or citrate modulates cell mobility in a 3D collagen matrix (the structural component).
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