癌症
气体分析呼吸
医学
呼吸试验
采样(信号处理)
乳腺癌
肺癌
前列腺癌
人口
肿瘤科
病理
内科学
计算机科学
滤波器(信号处理)
解剖
环境卫生
幽门螺杆菌
计算机视觉
作者
K. M. Mohibul Kabir,William A. Donald
标识
DOI:10.1080/13543776.2018.1423680
摘要
Human breath can contain thousands of volatile organic compounds (VOCs) and semi-volatile compounds that are related to metabolism and other biochemical processes. The presence of cancer cells can affect the identity and abundances of chemicals in breath when compared to those in healthy control subjects, which can be used to indicate the likelihood of a patient having cancer. Recently, the chemical analysis of exhaled breath from patients has been shown to be promising for diagnosing many different types of cancers, including lung, breast, colon, head, neck, and prostate, along with pre-cancerous conditions (dysplasia).Here, we reviewed the sampling, analytical and data analysis methods reported in the recent patent literature related to cancer breath testing (2014-2017). In addition, the different types of cancer biomarkers that were disclosed are discussed.The major advantages of breath testing compared to conventional X-ray and imaging based methods includes simplicity of use, non-invasiveness, and the potential to detect cancer at a relatively early stage. Such methods are also suitable to perform population screening because of their non-invasiveness. However, the establishment of standard sampling, detection and quantification methods for breath testing is required before the methods can be employed for clinical diagnosis.
科研通智能强力驱动
Strongly Powered by AbleSci AI