医学
重症监护医学
氟康唑
棘白菌素
侵袭性念珠菌病
心理干预
血液学
内科学
抗真菌
护理部
皮肤病科
作者
Caitlin Keighley,Louise Cooley,Arthur J. Morris,David Ritchie,Julia Clark,Peter Boan,Leon J Worth,Monica Slavin,Karin Thursky,Jason A. Roberts,Leon J Worth,Christina C. Chang,Sharon C‐A Chen,C. Orla Morrissey,Christopher Blyth,Anna Khanina
摘要
Patients with haematological malignancies, haemopoietic stem cell transplant recipients and patients requiring admission to intensive care settings are at high risk for invasive candidiasis (IC). Over the past decade, there has been increased reporting of non-albicans species and fluconazole resistance in Australia. These guidelines provide updated evidence-based recommendations for the diagnosis and management of IC in adult and paediatric haematology, oncology and intensive care settings. Optimal pharmacological and non-pharmacological management are discussed. Recent studies strengthen the recommendation for an echinocandin agent as first-line therapy for high-risk patients with IC. Mortality benefit has also been demonstrated for non-pharmacological management, including removal of central venous catheters, infectious diseases consultation and use of care bundles. Healthcare facilities managing immunocompromised patient populations should therefore adopt implementation strategies for these multimodal interventions.
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