生物
癌症研究
基因
表观遗传学
DNA甲基化
有丝分裂
癌症
细胞周期
机制(生物学)
甲基化
遗传学
作者
Lin Yuan,Zhenyu Yang,Jing Zhao,Tao Sun,Chunyu Hu,Zhen Shen,Guanying Yu
标识
DOI:10.3389/fgene.2022.893358
摘要
Ubiquitin-Conjugating Enzyme E2 C (UBE2C) is a gene that encodes protein. Disorders associated with UBE2C include methotrexate-related lymphatic hyperplasia and complement component 7 deficiency. The encoded protein is necessary for the destruction of mitotic cell cyclins and cell cycle progression, and may be involved in cancer progression. In this paper, on the basis of public databases, we study the expression differential mechanism of gene expression of UBE2C in various tumors and the performance of prognosis, clinical features, immunity, methylation, etc.
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