Big Data on Gastric Dysplasia Support Gastric Cancer Prevention

As in other cancer settings, strategies for preventing gastric cancer (GC) demand a multimodal approach. A recent thorough study by Xiao et al1 addresses the heterogeneous spectrum of epidemiologic, biologic, clinical, and operative variables involved in advanced gastric precancerous lesions. Because of the peculiar clinicopathologic setting of “cardia” precancerous lesions (<1% in the Xiao et al1 study), this editorial focuses, in particular, on the important contribution of the Chinese study on the “proper gastric” advanced precancerous lesions.