医学
活性成分
安慰剂
成分
光老化
皮肤护理
皮肤病科
皮肤老化
敏感皮肤
皮肤干燥
功能性食品
膳食补充剂
食品科学
药理学
化学
病理
替代医学
护理部
作者
Federica Carlomagno,Gloria Roveda,Angela Michelotti,Federica Ruggeri,Francesco Tursi
出处
期刊:Cosmetics
[MDPI AG]
日期:2022-05-27
卷期号:9 (3): 54-54
被引量:7
标识
DOI:10.3390/cosmetics9030054
摘要
Hyaluronic acid (HA) has long been used for its anti-age properties, as an ingredient in both topical applications and food supplements. In this study, a novel sodium hyaluronate, based on the innovative full spectrum technology, was administered as an ingredient of a cosmetic product and as the main constituent of a food supplement to evaluate its efficacy in counteracting skin ageing signs. Seventy-five female subjects were randomly assigned to the following treatments for 4 weeks: an active food supplement and a placebo cosmetic product, an active cosmetic product and a placebo food supplement, and a combination of the two products containing the active ingredient, that is, an “In&Out” treatment. The subjects used the placebo cosmetic product for another 14 days. Improvement of all the outcome measures (skin moisturization, elasticity, firmness and profilometry) was achieved by all treatments (p < 0.05); however, the combined treatment resulted in a further amelioration of the skin aging signs with respect to the two single active treatments (p < 0.001), and such effect lasted also after the follow-up period. In conclusion, such results confirmed that the concomitant administration of hyaluronans by these two different routes represents more than an interesting approach to counteract skin aging signs.
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