生物过程
生化工程
生物过程工程
生物量(生态学)
发酵
生物反应器
无氧运动
生物技术
代谢工程
生产(经济)
产量(工程)
生产力
制浆造纸工业
生物
工程类
食品科学
生物化学
生态学
化学工程
植物
材料科学
生理学
宏观经济学
冶金
经济
酶
作者
Julian Lange,Ralf Takors,Bastian Blombach
标识
DOI:10.1002/elsc.201600108
摘要
Microbial fermentation of renewable feedstocks is an established technology in industrial biotechnology. Besides strict aerobic or anaerobic modes of operation, novel innovative and industrially applicable fermentation processes were developed connecting the advantages of aerobic and anaerobic conditions in a combined production approach. As a consequence, rapid aerobic biomass formation to high cell densities and subsequent anaerobic high‐yield and zero‐growth production is realized. Following this strategy, bioprocesses operating with substantial overall yield and productivity can be obtained. Here, we summarize the current knowledge and achievements in such microbial zero‐growth production processes and pinpoint to challenges due to the complex adaptation of the cellular metabolism during the cell's passage from aerobiosis to anaerobiosis.
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